Sorry, no you can't. Assuming this is a gape vine it needs to be pruned hard in mid-winter when the sap is down in the roots. If you prune now it will bleed sap profusely

If you're not speaking about a grapevine, what plant do you mean ?

I wonder if its Virginia creeper as she says she is painting the house.
well it will have to chances,live or die, if you have to cut it down now.